Who must check and sign orders for Schedule II controlled substances when received?

The correct choice is that a pharmacist must check and sign orders for Schedule II controlled substances when received. This requirement is in place because Schedule II substances are highly regulated due to their potential for abuse and addiction. The pharmacist has the necessary training and authority to assess the appropriateness of the order, ensuring that it meets all legal, safety, and therapeutic guidelines before it can be dispensed.

Pharmacists are responsible for verifying the accuracy of the medication orders, including checking the dosage, route of administration, and the patient's medical history. This process helps to prevent errors that could lead to significant health risks.

In contrast, certified pharmacy technicians and pharmacy technicians assist in various pharmacy operations but do not have the legal authority to verify and sign orders for controlled substances. Third parties, such as insurance companies or other external entities, do not play a role in the direct handling or verification of these orders within the pharmacy setting. Therefore, the responsibility for checking and signing orders for Schedule II controlled substances rightly falls on the pharmacist.