What does the term 'buccal' refer to in medication administration?

The term 'buccal' refers specifically to the administration of medication between the gums and the inner lining of the cheek. This route allows the medication to be absorbed directly into the systemic circulation through the buccal mucosa, providing a rapid onset of action without the need for swallowing or injection.

The distinction of buccal administration is significant as it differs from other routes. For example, sublingual administration (often confused with buccal) refers to placing medication under the tongue, which also allows for rapid absorption but through a different anatomical area. Intradermal and subcutaneous routes involve injection techniques into the skin layers or subcutaneous tissue, respectively, which is not applicable to buccal administration at all. Thus, 'inside of the cheek' accurately captures the specific site of buccal drug delivery.