_____________________ literature contains general reference works based upon primary literature sources.

The correct answer, which identifies literature that contains general reference works based upon primary literature sources, is tertiary literature. Tertiary literature typically includes compilations, summaries, and distillations of information drawn from primary and secondary sources. For example, tertiary sources can encompass textbooks, encyclopedias, and databases that provide a comprehensive overview of a particular topic by synthesizing existing information.

In contrast, primary literature refers to original research studies and firsthand reports of data, while secondary literature involves analyses and interpretations of primary sources. Therefore, tertiary literature serves as a crucial resource in pharmacy and related fields, as it condenses large amounts of information into accessible formats that are useful for both practitioners and students. This makes it essential for quick reference and broad understanding without delving into the complexities of the original studies.